MorpheusML is an innovative, globally adopted, open-source, community-driven modelling and simulation framework for studying multiscale and multicellular systems. It enables the modelling of complex biological systems at the cellular level, taking into account spatio-temporal and mechanical aspects. Such biological systems include self-organisation, patterning, morphogenesis and disease processes from the intracellular to the tissue and organ level. Applications include systems biology, biophysics and systems medicine.

The Centre for Interdisciplinary Digital Sciences (CIDS) at TUD Dresden University of Technology is committed to providing the global research community with a standard for the computer-readable definition called MorpheusML that enables the modelling of complex biological systems.

This is achieved in conjunction with the MorpheusML Model Repository, which is a public, freely accessible platform that collects, curates, documents, tests and validates computational biological models, enabling their FAIR publication.

The workshop addresses digital resilience by strengthening the robustness, interoperability, discoverability, and long-term sustainability of models, simulation environments and research infrastructures. This is achieved through open standards for research data, software and other scientific outputs, FAIR practices as well as community-driven Trustworthy Digital Repositories (TDRs) and their certification.

At the 2026 Informatik Festival, the MorpheusML workshop will cover three main topical areas:

1. Multicellular modelling standard design and model implementations.
   2. Repositories, FAIR publication and certification, including aspects such as metadata formats, standardised annotations and repository interconnection.
   3. Community work within the biological and medical research community to promote the exchange across relevant modelling formalisms, simulation environments, repository providers and networks.

Workshopchairs:

• Diego Jahn
• Dr. Lutz Brusch